Swedish researchers involved in a long term study of 1201 women have suggested that the apparent benefits to the heart of HRT could be explained by the better health enjoyed by women who choose to take it.
Oestrogen Replacement Therapy (HRT) has an adverse effect on Vitamin B levels. Perhaps all women taking HRT should consider supplementing with Vitamin B to counteract this problem. (Journal of American Coll. Nutrition; 1993; 12; pp 442-58)
According to the International Menopause Society, the two biggest studies into the effects of HRT that took place in 2002 and 2003 were deeply flawed and had caused a massive knee jerk reaction which has lead to millions of women abandoning HRT and to thousands of doctors refusing to prescribe it.