Increased risk of dementia following removal of the ovaries

1500 Women in a 30-year follow-up study who had ovaries surgically removed before menopause had nearly double the risk for developing age-related dementia later in life.   However, this increase in risk was not seen in women who had both ovaries removed and were also treated with oestrogen until at least age 50.

The study, published in the latest online issue of the journal Neurology, suggests there is a “critical age window” for the protective effect of oestrogen on women’s brains, says researcher Walter A Rocca, MD, MPH, of the Mayo Clinic in Rochester, Minn.

“It is possible that oestrogen has a protective effect on the brain and that lack of estrogen due to ovary removal may increase a woman’s risk of developing memory problems,” Rocca says in a news release.

You can read more at the WebMD website


  1. My mum had hysterectomy when she was in her late thirties back in the sixties, and at that time she didn’t receive any HRT replacement back then , I do believe that there is the reason why she developed Alzheimers when she was in her early sixties , I know of another lady who was in the same situation as my mum who had her uterus removed again to develop Alzheimers later in her life at the age of early sixties , as it is proved that the ovaries stops functioning few years after removal of the uterus. These are only two proven cases and I believe there is a very strong relation between Alzheimers and early hysterectomy , I wish my mum didn’t do this operation and wouldn’t suffer.

  2. My mother had a hysterectomy, her ovaries and cervix were removed when I was 11, my mum died that day. She turned into a frightening aggressive person, who lost her identity. She stole mine and best part of 20 years of my life have been taken by this person who I can’t call mum anymore. She has ruined my life and is trying her best to ruin my children. The emotional effect of this operation causes post traumatic stress disorder and needs looking into as I have witness first hand how it can destroy people’s lives

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