Swedish researchers involved in a long term study of 1201 women have suggested that the apparent benefits to the heart of HRT could be explained by the better health enjoyed by women who choose to take it.
They showed that the women using HRT had significantly less obesity and lower blood pressure than those not taking HRT indicating that the HRT users were at an advantage before treatment began. (BMJ; 2000; 319; pp 890 – 893)
In addition, other researchers have indicated that women taking HRT are more likely to have higher levels of CRP (C-Reactive Protein) levels which is a chemical marker for systemic inflammation, suggesting that they may be at an increased risk of vascular (heart) inflammation.
(Circulation; 1999; 100; pp 713 – 6)