The women’s Health Initiative has suggested that oestrogen only hrt should not be used for chronic disease prevention in post menopausal women. However oestrogen only does appear to show less long-term risk than the use of oestrogen and progesterone. The women’s Health Initiative Steering Committee. Effects of conjugated equine oestrogen in post menopausal women with hysterectomy. The women’s Health Initiative randomized controlled trial. Women who have had a hysterectomy will almost certainly only be offered oestrogen only versions of HRT. JAMA 2004 Apr 14 291 pp1701-12.